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MCP server · Code & DevOps

Folklore Clinical Variant Interpretation MCP

By helena-bioinformatics Verified namespace

Germline ACMG/AMP classification, genes, disease associations, literature and API-key case analysis.

WebsiteSource codeHealth & science
Connect to Folklore Clinical Variant Interpretation MCP
Checks passed
15 / 22

0 failed · 7 not measured

Median response
106 ms

Median of successful probes over 7 days

30-day uptime
Not measured

Share of countable probes over 30 days, including daily rollups. Auth challenges are excluded.

Discovered tools
11

Tool definitions returned by this server

Independent monitoring

Health & checks

Status history

Responded

The server completed its last measured handshake. This is an observation, not a guarantee.

Last checked
Check summary by test group
Test areaPassedFailedUnmeasured
ConnectionCan a client connect and discover tools?
500
Reliability & speedDoes it respond consistently and quickly?
103
Access & authenticationWhat is required to use this server?
102
Tool qualityAre the tool definitions usable by an agent?
400
Publisher identityCan the publisher be traced to its source?
402

Unmeasured means there is not enough evidence to decide. How these checks work

Inspect individual checks 22 recorded

Core

  • Pass
    Reachable

    Latest probe returned HTTP 200 in 157 ms.

  • Pass
    Valid handshake

    protocolVersion 2025-11-25, serverInfo.name folklore.

  • Pass
    Lists tools

    tools/list returned 11 tools.

  • Pass
    Current protocol

    Negotiated 2025-11-25. The bar is 2025-06-18 or newer.

  • Pass
    HTTPS

    The endpoint URL is https.

Performance

  • Not measured
    Fast (p50)

    Median latency 106 ms over 2 samples in 7 days. The bar is 1000 ms. Need at least 5 samples.

  • Not measured
    Consistent (p95)

    95th percentile 152 ms over 2 samples in 7 days. The bar is 3000 ms. Need at least 20 samples.

  • Not measured
    Reliable (uptime)

    2 of 2 attempts returned a tool list in 30 days (100%). The bar is 99%. Need at least 30 samples.

  • Pass
    Stable tool list

    No tool was removed and no required parameter was added in the last 30 days.

Access

  • Pass
    Open access

    tools/list succeeded with no credential, and the record declares none.

  • Not measured
    Standard auth

    Auth is not required, so the OAuth metadata check does not apply.

  • Not measured
    Free tier cited

    No publisher quote has been checked.

Tools

  • Pass
    Tools described

    Every tool description is at least 20 characters.

  • Pass
    Valid input schemas

    Every inputSchema is a JSON Schema object.

  • Pass
    Parameters documented

    30 of 30 parameters have a description (100%). The bar is 80%.

  • Pass
    Safety hints

    Every tool sets readOnlyHint or destructiveHint.

Publisher

  • Pass
    Verified namespace

    Listed in the Official MCP Registry.

  • Not measured
    Website matches publisher

    This namespace is not a reverse domain, so the website comparison does not apply.

  • Pass
    Source repo linked

    A repository URL is on file.

  • Pass
    Repo owner matches

    The GitHub repository owner matches the namespace login.

  • Pass
    Recently updated

    Updated 2026-11-05T23:16:26.332615Z, within 180 days.

  • Not measured
    Open-source licence

    The GitHub licence lookup has not returned an OSI result yet.

Start using Folklore Clinical Variant Interpretation MCP

Connect to this server

Choose your client, copy the configuration, then enable the server in your client’s MCP settings.

Run this command in your terminal, then restart Claude Code.

Claude Code

claude mcp add --transport http folklore-clinical-variant-interpretation-mcp https://api.helena.bio/folklore/v1/mcp

Capabilities

Tools 11

classify_germline_variant

Classify one GRCh38 germline nuclear SNV or simple indel smaller than 50 bp under ACMG/AMP. Accepts genomic, coding or protein HGVS, coordinates, SPDI, rsID or a returned canonical key. Returns normalized identity, automated classification, applied criteria, ClinVar assertions, population frequencies, annotations and source provenance when available. Ambiguous input returns candidates for selection.

Discovered
get_gene_disease_associations

Find diseases associated with an exact gene symbol or HGNC identifier. Returns ClinGen gene-disease validity assertions, relation-specific inheritance, source reports and snapshot provenance, including conflicting and limited assertions.

Discovered
get_gene_profile

Read the selected gene_id and immutable snapshot_id from resolve_gene. Returns overview, disease validity, dosage, mechanisms, transcripts, native assemblies, constraint, ClinVar summaries and consequences, expression, GWAS, phenotypes and protein/pathways with source assertions, coverage, count units and null values. get_gene_section supplies further pages. Live search_gene_literature is separate from the snapshot literature section.

Discovered
get_gene_section

Read a gene-profile section using gene_id, snapshot_id and its returned opaque cursor. Returns source records, assembly/release, coverage, totals, count units and provenance. snapshot_unavailable requires a fresh resolution/profile request.

Discovered
get_publication_details

Retrieve one PMID from the PubMed-derived genetics corpus, including title, abstract, authors, journal, publication types, MeSH terms, gene and variant mentions, retraction status and PubMed/PMC links.

Discovered
resolve_gene

Resolve a human gene symbol, previous symbol, alias, HGNC, Ensembl or NCBI Gene identifier. Returns exact, alias, ambiguous, not_found or withdrawn status with candidates and identity_snapshot_id. Use a selected HGNC gene_id and snapshot_id with get_gene_profile. Gene-plus-HGVS and variant expressions use classify_germline_variant.

Discovered
search_disease_genes

Find genes associated with an exact MONDO identifier or disease-name search. Returns ClinGen validity assertions with inheritance, source reports and snapshot provenance. Name searches can return multiple disease identities.

Discovered
search_gene_literature

Retrieve a live publication capture for a resolved gene_id and snapshot_id. Returns source links, match labels, capture time/hash, degradation and gene/snapshot/sort-bound cursors. This capture is separate from the immutable reference snapshot and contains no abstracts.

Discovered
search_literature_corpus

Search the genetics Literature Corpus by question, PMID, DOI, PMCID, gene, variant, phenotype, HPO or OMIM concept. Known publication identifiers provide exact anchors. Returns ranked publications, match types, scores and source links.

Discovered
search_variant_literature

Resolve one GRCh38 germline variant and retrieve publications from the PubMed-derived genetics corpus. Exact variant mentions rank ahead of broader gene associations. Returns match types, source links, corpus provenance and retrieval time.

Discovered
support_helena

Retrieve Helena Good campaign, rules, manifest and MCP connection URLs.

Discovered

Recent measurements

Probe history

View status
Latest stored probes. Raw probe rows are kept for 14 days.
CheckedResultResponseTools
Connected157 ms11
Connected55 ms11

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