GreenCycle Compound Atlas

Use when you have a plain question such as "does CBD help epilepsy", "where does THC act" or "what binds TRPV1": the best first call, one argument. It finds the compounds, conditions and receptors the question names in Greencyclepedia and answers only from those records: the evidence grade, the key findings with PubMed identifiers, the Greencyclepedia pages, a not medical advice line and cite_as (title, url, licence, accessed date). When the question names nothing Greencyclepedia holds, it says so and suggests the closest names and tools. Educational reference, not medical advice. No doses. Example arguments: {"question":"does CBD help epilepsy"}.

Use when you are about to quote or link Greencyclepedia and need the citation. A ready citation for one Greencyclepedia record (compound, target or condition) or for Greencyclepedia as a whole: the canonical url, the citation line, a BibTeX entry, the version, the original papers to cite for its findings (PubMed links) and the licence (CC BY 4.0 with attribution). Example arguments: {"id":"compound:cbd"}.

Use when asked "THC versus CBD" or a similar comparison. Two to four compounds side by side, target by target, with each action, evidence grade, measured binding values and PubMed identifiers, the targets they share and the Greencyclepedia comparison page when one exists. Educational reference, not medical advice. Not a ranking of which is better for anyone. Example arguments: {"ids":["thc","cbd"]}.

Use when search has returned an id and you want the whole record. The full text of one Greencyclepedia record by the id that search returned ("compound:cbd", "target:CB1", "condition:epilepsy", "trial:NCT03883360", "cultivar:STRAIN0001"): what it is, the targets and effects with evidence grades, measured binding values, cautions, every source (PubMed ids with links) and the citation line, with the Greencyclepedia url. Educational reference, not medical advice. No doses. Example arguments: {"id":"compound:cbd"}.

Use when asked "what is the evidence" or "which studies". The PubMed studies Greencyclepedia cites for a compound, a target, a condition or a compound at one target, each with its PubMed link, what it supports (an effect at a target, a binding value, a caution, a systematic review or a trial as administered) and the Greencyclepedia record it belongs to, plus the PubMed search behind each record. Doses are left out on purpose. Educational reference, not medical advice. Example arguments: {"compound":"cbd","condition":"epilepsy"}.

Use when you need to know what is new or whether the data changed since you last looked. The latest releases of the Greencyclepedia data files: the version to cite, which datasets changed, records added and removed, and where the dated copy of each release lives, plus new_sources: the news sources and partners added in the last 30 days, with the date added and what each covers. Example arguments: {"limit":3}.

Use when asked "what does THC, CBD or myrcene do in the body". The full record of one mapped compound by Greencyclepedia id, Cannabis Compound Database id, name or PubChem CID. A curated record gives identity and structure identifiers, every target with the action, effect, evidence grade, body structures and PubMed identifiers, the measured binding values (pKi, pIC50, pEC50) from the IUPHAR/BPS Guide to PHARMACOLOGY, the cultivars a laboratory measured it in with their sources, an evidence summary, its cautions and a ready citation. A database compound gives its identity and every measured value at a placed target with its PubMed id or DOI. Educational reference, not medical advice. No doses. Example arguments: {"id":"cbd"}.

Use when asked about the chemistry of a strain or cultivar. One cultivar from the laboratory measurements Greencyclepedia uses (Cannabis Compound Database values, mg per gram of dry flower), by CCD id or name: every Greencyclepedia compound measured in it with the mean, the number of values and the PubMed identifier of each source. Cultivar names are a poor guide to chemistry (PMID 35588111, PMID 39137353); never the community strain index. Educational reference, not medical advice. Example arguments: {"id":"STRAIN0001"}.

Use when asked about a receptor, channel or enzyme. One receptor, ion channel or enzyme by name or gene (for example CB1, CNR1, TRPV1, GPR55, FAAH, CYP3A4): what it is, where it sits in the body, the compounds mapped to it with their action, effect and evidence grade, and every measured binding or functional value with species and PubMed identifiers, plus the measured 3D structure (the PDB entry, method, resolution, organism, paper, licence, a viewer link and a still picture) or "No measured structure yet". Educational reference, not medical advice. Example arguments: {"id":"CB1"}.

Use when asked "where in the body". The body map structures (organs and regions) that carry a molecular target: for CB1 and CB2 the qualitative receptor density (0 to 4, a teaching summary of the literature, not a measurement), other receptors listed for a structure, and the structures where a compound effect at this target is mapped, with the compound and its evidence grade, and the measured 3D structure of the target (entry, method, resolution, organism, paper, licence, viewer link, still picture) or "No measured structure yet". Educational reference, not medical advice. Example arguments: {"target":"CB1"}.

Use when asked about clinical trials. Registered trials from the Greencyclepedia snapshot of ClinicalTrials.gov (trials whose intervention is named cannabis, a cannabinoid, cannabidiol, THC or a related medicine): identifier, title, status, phase, enrolment, conditions, countries, start date, the Greencyclepedia compounds involved and the registry link, newest snapshot first. Intervention names that state an amount are left out. Titles are third party text. Educational reference, not medical advice. Example arguments: {"query":"epilepsy","limit":5}.

Use when asked about the cannabis market or industry figures. Facts from cannabis industry news in our own words, each with its number, the data source the article names (or "no source named") and a link to the publisher. Market context, not medical evidence. Newest article first; replaced figures are left out unless asked for. Example arguments: {"limit":5}.

Use when you do not know the exact name or id, or want to see what Greencyclepedia holds on a topic. Search all of Greencyclepedia by any name: cannabis compounds (THC, CBD, CBG, terpenes, flavonoids), receptors and enzymes (CB1, CB2, TRPV1, 5-HT1A, FAAH), medical conditions with an evidence grade (epilepsy, chronic pain, sleep) and registered clinical trials. Returns results with id, title and url; pass an id to fetch for the full sourced record. Educational reference, not medical advice. Example arguments: {"query":"cannabidiol"}.

Use when you need a list of cannabis compounds, for example every compound at CB2 or every terpene. Find the compounds mapped onto the human body (curated Greencyclepedia records and database compounds with a measured, sourced value at a target placed in tissue) by name, chemical class, record type or molecular target (for example every compound acting at CB2, TRPV1, 5-HT1A or FAAH, or every terpene). Returns identity, PubChem CID, record type, targets and the Greencyclepedia url. Use get_compound for one full record. Educational reference, not medical advice. Example arguments: {"target":"CB2","limit":10}.

Use when asked "does cannabis help with ...". Conditions on the Greencyclepedia evidence ladder (substantial, moderate, limited, insufficient, evidence of no benefit): the grade and why, the systematic reviews and trials behind it by PubMed identifier, the compounds and body structures involved and the Greencyclepedia page. Trials are kept as administered in each trial; doses are left out on purpose. Educational reference, not medical advice. Not a diagnostic or dosing tool. Example arguments: {"query":"sleep"}.

Use when asked "how much research is there on the thorax" or "which body parts have no studies yet". The Studies per body part key of the Greencyclepedia body map. Give a region (head-neck, thorax, abdomen, pelvis, upper-limb-left, upper-limb-right, lower-limb-left, lower-limb-right) or leave it out for the whole body: the parts by study band (No studies yet, 1 to 99, 100 to 999, 1,000+) with counts, the most studied parts, the parts with no studies yet, the snapshot date, the source and licence and the body map link. A count is the PubMed studies that name the part, from a weekly saved snapshot. Educational reference, not medical advice. Example arguments: {"region":"thorax"}.